New Invention: Laser Scanner that Detects Malaria Infections in Seconds

Researchers have developed the first non-invasive method of detecting malaria infection using a laser beam scanner. The painless test appears to be 100 percent accurate and does not require using any blood. Currently, the gold standard of malaria testing is examining a blood smear under the microscope for evidence of the deadly parasite. A diagnosis requires trained technicians, expensive equipment and time, things that are not always available in poorer and more remote parts of the world. But so-called "vapor nanobubble" technology would eliminate the need to draw any blood. It only requires an individual to place a finger on a laser device, according to Dmitri Lopotko, a researcher with the department of biochemistry and cell biology at Rice University in Houston, Texas. "We shine a very short light pulse through the skin.  And this light pulse is absorbed only by malaria parasites because of the wavelength we use. And in response to this short light pulse, the parasite literally explodes," he said.

A possible rapid, non-invasive test for malaria infection detects tiny vapor nanobubbles produced by the malaria parasite when it is zapped by a short laser pulse. (Rice University)
The portable battery-powered device won't  be cheap, however, costing around $10,000-$20,000 each to manufacture. "But each device will be capable to screen more than 200,000 people per year. So the cost of analysis for each patient will be less than 50 cents," he said. And it can be used by non-medical personnel to diagnose suspected cases of malaria. Lopotko said the light beam used by this rapid, non-invasive technology is less powerful than the familiar laser pointer and has been shown to be safe in volunteers. The next step is clinical trials at a hospital in Houston that cares for patients infected with malaria, followed shortly thereafter by global clinical trials in 2014.